Does Mayweather's jail sentence KO his shot at Pacquiao?

Floyd Mayweather Jr. likes to say it all the time: 42 men have tried, but 42 men have failed. 

In the ring, Mayweather is 42-0 with 26 knockouts, having never lost a bout.

But on Wednesday, one very powerful woman may have succeeded where all those men have come up short.

Click here for a TMZ video of Mayweather's sentencing.

Las Vegas Justice of the Peace Melissa Saragosa sentenced the five-division titleholder to 90 days in jail starting on January 6, also ordering him to pay a $2,500 fine, to complete 100 hours of community service and to undergo 12 months of treatment in a domestic violence program as a result of Wednesday's guilty plea to a charge of misdemeanor battery domestic violence and no contest on two counts of harassment.

The 34-year-old veteran is coming off a fourth-round knockout of Victor Ortiz in September that earned him the WBC's welterweight title belt, and had targeted a return to the ring on May 5 against an opponent to be determined, potentially WBO welterweight beltholder Manny Pacquiao.

Does Saragusa's verdict KO Mayweather-Pacquiao?

Although it is uncler how the sentencing affects the future of Mayweather, Kevin Iole of Yahoo! Sports takes a stab at assessing the damage, pointing out that the sentence coincides with the time Mayweather would need to train for a May 5 fight.

He goes on to say that Mayweather's age (he'll turn 35 in February) might prevent him from bouncing back quickly from a prison stint as other, younger fighters -- like Mike Tyson -- have in the past.

Read Kevin Iole's full story here.

Lem Satterfield can be reached at lemuel.satterfield@gmail.com